Why is pcos associated with obesity




















J Clin Endocrinol Metab 84 : — Diabetologia 28 : — Hum Reprod 19 : 41 — J Clin Endocrinol Metab 89 : — Legro RS Polycystic ovary syndrome and cardiovascular disease: a premature association? Endocr Rev 24 : — Solomon CG The epidemiology of polycystic ovary syndrome. Prevalence and associated disease risks. Endocrinol Metab Clin North Am 28 : — Postgrad Med J 69 : — J Clin Endocrinol Metab 83 : — Annu Rev Nutr 21 : — Oxford University Press is a department of the University of Oxford.

It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Sign In. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents Subjects and Methods.

Oxford Academic. Select Format Select format. Permissions Icon Permissions. Settings: The study was performed at an academic hospital. Interventions: Bariatric surgery was performed. TABLE 1. Age yr Open in new tab. Open in new tab Download slide. First Published Online September 27, A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. Google Scholar PubMed. Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries.

Google Scholar Crossref. Search ADS. The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. Effects of diet and metformin administration on sex hormone-binding globulin, androgens, and insulin in hirsute and obese women.

Overweight and obese anovulatory patients with polycystic ovaries: parallel improvements in anthropometric indices, ovarian physiology and fertility rate induced by diet. Weight loss results in significant improvement in pregnancy and ovulation rates in anovulatory obese women. Insulin sensitizers and antiandrogens in the treatment of polycystic ovary syndrome.

Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. Diagnostic criteria for polycystic ovary syndrome: Towards a rational approach. Boston: Blackwell;. Screening for hydroxylase-deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study.

Treatment of hirsutism with ethinyl estradiol-desogestrel contraceptive pills has beneficial effects on the lipid profile and improves insulin sensitivity. A critical evaluation of simple methods for the estimation of free testosterone in serum. Revised consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome PCOS. Evidence for an association between metabolic cardiovascular syndrome and coronary and aortic calcification among women with polycystic ovary syndrome.

Polycystic ovary syndrome and cardiovascular disease: a premature association? Women diagnosed for PCOS also undergo blood tests that measure levels of several hormones in order to exclude potential causes of menstrual abnormalities or androgen excess. Quitting smoking is generally the most positive action you can take to improve your health, and related to PCOS, it may lower the higher levels of androgens.

Birth control pills and androgen reducing therapies can address the symptoms of PCOS, such as menstrual cycle problems, male-type hair loss and hair growth and acne. For women who wish to get pregnant, fertility drug treatment may also help start ovulation. For some women, a doctor might also prescribe the anti-diabetic drug metformin, or the fertility drug gonadotropins, to address insulin resistance. And importantly, even modest weight-loss of 5 to 7 percent of body weight throughout six months can lower your insulin and androgen levels.

Such a reduction, according to Dr. As with any chronic disease, finding it early helps a lot. These include high blood pressure, type 2 diabetes, sleep apnea, abnormal uterine bleeding, cholesterol abnormalities, metabolic syndrome, heart disease, cancer of the uterus and complicated pregnancies. With early diagnosis and treatment of PCOS, doctors can reduce risk of these long-term complications.

No simple cure for PCOS exists. Fortunately, it can be controlled, decreasing the risk of long-term complications. Engaging in regular exercise, keeping a healthy diet, losing excess weight, quitting smoking and using medications to control hormones are all important parts of treatment for PCOS. Furthermore, it is important to fuel your body with a healthy diet — one that includes many complex carbohydrates and is low in animal fats.

The more fiber in a food, the slower it is digested, which has the advantage of causing your blood sugar levels to rise slower. Examples of high-fiber complex carbohydrates include whole-grain breads and cereals, whole-wheat pasta, brown rice, barley and beans.

PCOS is a common hormonal disorder that affects women of reproductive age. PCOS challenges the quality of life of the women who suffer from it. Yet with proper treatment, PCOS can be managed and symptoms can be relieved. In addition, early diagnosis and treatment of PCOS can help reduce the risk of long-term complications such as type 2 diabetes, heart disease and stroke.

Ted has worked for more than 10 years on programs and products to help people quit smoking and lose weight. Fortunately, many treatments can help women with PCOS get pregnant. One factor that contributes to excess androgen production is insulin resistance. When the body cannot use insulin properly, it increases glucose production, which may increase androgen production by the ovaries. Insulin resistance can also lead to weight gain and difficulty losing weight. Weight gain increases the risk of high blood pressure, type 2 diabetes, sleep apnea, and heart disease.

The heavier you are, the greater your health risks. Losing weight, even just 5 percent of your body weight, can help reduce the symptoms and risks of PCOS. Treatment options include:. If you have endometriosis, your periods may be heavy, painful, and debilitating. Weight gain. Skipped periods.



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